US regulations regarding the Environment are written by the Environmental Protection Agency. Their role is to write regulations that explain the technical, operational, and legal details necessary to implement laws. Regulations are mandatory requirements that can apply to individuals, businesses, state or local governments, non-profit institutions, or others. The EPA publishes guidelines to demostrate how to comply with their regulations and actively seeks participation from interested parties in the formation of and excerising of such rules.

The EPA has ten Regional offices, each of which is responsible for the execution of their programs within several states and territories.

* Region 1 – Boston (serving Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont)
* Region 2 – New York (serving New Jersey, New York, Puerto Rico, and the U.S. Virgin Islands)
* Region 3 – Philadelphia (serving Delaware, District of Columbia, Maryland, Pennsylvania, Virginia, and West Virginia)
* Region 4 – Atlanta (serving Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee)
* Region 5 – Chicago (serving Illinois, Indiana, Michigan, Minnesota, Ohio, and Wisconsin)
* Region 6 – Dallas (serving Arkansas, Louisiana, New Mexico, Oklahoma, and Texas)
* Region 7 – Kansas City (serving Iowa, Kansas, Missouri, and Nebraska)
* Region 8 – Denver (serving Colorado, Montana, North Dakota, South Dakota, Utah, and Wyoming)
* Region 9 – San Francisco (serving Arizona, California, Hawaii, Nevada, American Samoa, Commonwealth of the Northern Mariana Islands, Federated States of Micronesia, Guam, Marshall Islands, and Republic of Palau)
* Region 10 – Seattle (serving Alaska, Idaho, Oregon, and Washington)